The DNA, RNA, and protein metabolism section includes posts covering DNA replication, DNA repair, DNA metabolism, RNA transcription and processing, protein synthesis, protein modification, synthesis of glycoproteins, and the turnover of proteins, organelles, and cells
Last Modified: March 5, 2024 Protein Activation via Proteolytic Cleavage Most proteins undergo proteolytic cleavage following translation. The simplest form of this is the removal of the initiation methionine. Many proteins are synthesized as inactive precursors that...
Last Updated: November 20, 2023 Protein Folding: Co- and Post-translational Processing The process of protein synthesis, of and by itself, does not directly result in the generation of functionally and structurally complete macromolecules. Many proteins must undergo...
Last Updated: February 22, 2024 Introduction to Processes of Protein, Organelle, and Cell Turnover During the normal course of cellular life macromolecules serve their intended purposes and must be degraded or turned over to ensure their function(s) remain tightly...
Last Updated: February 7, 2024 Introduction to Glycoproteins Membrane associated carbohydrate is exclusively in the form of oligosaccharides covalently attached to proteins forming glycoproteins, and to a lesser extent covalently attached to lipid forming...
Last Updated: January 24, 2024 Introduction to Translation Translation is the RNA directed synthesis of polypeptides (proteins). This process requires all three classes of RNA. Although the chemistry of peptide bond formation is relatively simple, the processes...
Last Updated: February 7, 2024 Introduction to RNA and the Processes of Transcription Transcription is the mechanism by which a template strand of DNA is utilized by specific RNA polymerases to generate one of the four distinct classifications of RNA. These four RNA...
Last Updated: February 23, 2024 Introduction to DNA Structure, Functions, and Replication All cells undergo a division cycle during their life span. Some cells are continually dividing (e.g. stem cells), others divide a specific number of times until cell death...