Diseases and Disorders, Disorders of Red Blood Cells
Last Updated: October 28, 2025 Introduction to the (beta) β-Thalassemias The human β-globin gene cluster is located on chromosome 11 (specifically 11p15.4) and includes the genes that encode the epsilon globin (ε: embryonic), the gamma A and gamma G globins (Aγ; Gγ:...
Diseases and Disorders, Disorders of Red Blood Cells
Last Updated: October 28, 2028 Introduction to the α-Thalassemias The thalassemias are the result of quantitative abnormalities in hemoglobin synthesis. With the α-thalassemias the level of α-globin production can range from none to very nearly normal...
Amino Acids and Proteins, Biochemistry Topics
Last Updated: November 12, 2025 Myoglobin and hemoglobin are hemeproteins whose physiological importance is principally related to their ability to bind molecular oxygen. Myoglobin is a monomeric heme protein found mainly in muscle tissue where it serves as an...
