Last Updated: December 5, 2024 Definition of Diabetes Diabetes is any disorder characterized by excessive urine excretion. The most common form of diabetes is diabetes mellitus, a metabolic disorder in which there is an inability to maintain carbohydrate and...
Insulin & Diabetes
The Insulin and Diabetes category includes posts/pages that discuss the details of insulin synthesis, processing, and function, the metabolic, pathophysiologic, and molecular aspects of type 1 and type 2 diabetes, and the pathology of diabetic ketoacidosis.
Diabetic Ketoacidosis: DKA
Insulin & Diabetes, Specialized Topics
Last Updated: December 19, 2022 Definition of Diabetic Ketoacidosis The most severe and life threatening complication of poorly controlled type 1 diabetes is diabetic ketoacidosis (DKA). DKA is characterized by metabolic acidosis (low pH of the blood),...
Dipeptidyl Peptidase 4: DPP4
Cellular & Molecular Biology, Insulin & Diabetes, Specialized Enzymes, Specialized Topics
Last Updated: March 2, 2023 Introduction to Dipeptidyl Peptidase Family Dipeptidyl peptidase 4 (DPP4; also DPP-4) is a member of the large family of proteases (peptidases). There are 10 protease families that are unique to higher organisms (16 protease families can be...
Insulin Function, Insulin Resistance, and Food Intake Control of Secretion
Insulin & Diabetes, Specialized Topics
Last Updated: December 12, 2024 Introduction to Insulin Activities Insulin and Metabolism Insulin is a major metabolism regulating hormone secreted by β-cells of the islets of Langerhans of the pancreas. The major function of insulin is to counter the concerted...