Disorders of Metal Transport and Metabolism

Last Updated: October 20, 2023 Introduction to Hemochromatosis Hemochromatosis is defined as a disorder in iron metabolism that is characterized by excess iron absorption, saturation of iron-binding proteins and deposition of hemosiderin (amorphous iron deposits) in...

Last Updated: March 6, 2023 Introduction to Wilson Disease Wilson disease (WD) is inherited as an autosomal recessive disorder of copper homeostasis. The disease is characterized by excessive copper deposition primarily in the liver and brain. These sites of copper...

Last Updated: March 6, 2023 Introduction to Menkes Disease Menkes disease is inherited as an X-linked recessive disorder of copper homeostasis. The disorder is associated with an inability to absorb copper from the gastrointestinal tract and an inability of tissues to...