Last Updated: December 3, 2024 Introduction to Mechanistic Target of Rapamycin: mTOR A central control complex that allows cells to respond and adapt to their particular environment is the Ser/Thr kinase identified as mTOR (mechanistic target of rapamycin). mTOR is...
Specialized Enzymes
The Specialized Enzymes category contains the posts/pages that detail the activities of the cytochrome P450 (CYP) enzymes utilized in a variety of biosynthesic processes as well as in xenobiotic metabolism reactions and the functions of dipeptidyl peptidase 4 (DPP4).
2-Oxoglutarate and Fe2+-Dependent Dioxygenases
Cellular & Molecular Biology, Specialized Enzymes
Last Updated: October 25, 2024 Introduction to the 2-Oxoglutarate and Fe2+ (FeII)-Dependent Dioxygenases The 2-oxoglutarate and Fe2+-dependent dioxygenases (often abbreviated 2OG-oxygenases or 2-OGDD) are a large family of enzymes that catalyze a broad range of...
Dipeptidyl Peptidase 4: DPP4
Cellular & Molecular Biology, Insulin & Diabetes, Specialized Enzymes, Specialized Topics
Last Updated: March 2, 2023 Introduction to Dipeptidyl Peptidase Family Dipeptidyl peptidase 4 (DPP4; also DPP-4) is a member of the large family of proteases (peptidases). There are 10 protease families that are unique to higher organisms (16 protease families can be...
Cytochrome P450 (CYP) Enzymes
Cellular & Molecular Biology, Specialized Enzymes, Specialized Topics
Last Updated: October 17, 2024 Introduction to Cytochrome P450 (CYP) Enzymes Enzymes of the cytochrome P450 (CYP) superfamily are all heme-containing enzymes. The term cytochrome P450 stems from the fact that the proteins are members of the cytochrome (heme...