Diseases Associated with Clotting Factor Dysfunction

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Afibrinogenemia complete loss of fibrinogen, Factor I

Dysfibrinogenemia dysfunctional fibrinogen, Factor I

Factor II Disorders

Factor III (tissue factor) is the only coagulation factor for which a congenital defect has not been identified

Factor V Deficiency Labile Factor deficiency

Factor VII Deficiency

Hemophilia A Factor VIII deficiency

Hemophilia B Factor IX deficiency

Factor X Deficiency

Factor XI Deficiency Rosenthal Syndrome, Plasma Thromboplastin Antecedent (PTA) deficiency

Factor XII Deficiency Hageman factor deficiency

Factor XIII Deficiency

Protein C Deficiency

Protein S Deficiency

Thrombophilia Antithrombin III deficiency

Glanzmann thrombasthenia platelet glycoprotein IIb-IIIa complex deficiency

Giant Platelet Syndrome: Bernard-Soulier Syndrome platelet glycoprotein Ib complex deficiency

von Willebrand Disease

Fletcher Factor Deficiency Prekallikrein deficiency

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Michael W. King, Ph.D / IU School of Medicine / miking at iupui.edu

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Last modified: November 2, 2009

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